Alzheimers Disease AD Pathology and Genetics Animation
Alzheimer's disease, or ad, is a very common neurodegenerative disorder in which brain cells are progressively damaged and die, leading to loss of memory, thinking skills and eventually all other brain functions.A brain consists of billions of neurons, or nerve cells, which communicate via chemical messages, or neurotransmitters.This communication occurs in a space between neurons, called a synapse.Neuron communication is essential to all brain activities.An alzheimer's brain is characterized by presence of abnormal plaques and tangles.Plaques are clumps of a peptide known as betaamyloid.Betaamyloid derives from a larger membrane protein normally present on the surface of.
Nerve cells.These clumps are toxic to nerve cells and may block celltocell signaling at synapses.They are also believed to trigger inflammation responses that bring further damage to the brain tissue.Tangles are formations of a protein named tau.Tau protein's major function is to stabilize axonal microtubules the tubular structures that run along axons of neurons and are responsible for intracellular transport.In ad patients, tau molecules are misfolded and clump into tangles.As a result, the microtubules are disintegrated and cellular transport is impaired.As the toxic deposits of plaques and tangles increase, neurons stop functioning, lose connections.
With each other, and die.The damage initially takes place in the hippocampus, the part of the brain that is essential in forming memories.That is why shortterm memory loss is usually one of the first symptoms of alzheimer's.Plaques and tangles tend to spread through the cortex in a predictable pattern as the disease progresses.New symptoms appear accordingly and in an order that corresponds to different stages of the disease.At the final stage, the brain shrinks dramatically and nearly all its functions are affected.Most people with alzheimer's show first symptoms after the age of 65, while the process.
Of neuron destruction has probably started many years earlier.For this form of lateonset ad, the cause remains largely unknown, but a combination of environmental and genetic factors is likely.Notably, a certain form of a lipoprotein named apolipoprotein e is shown to increase susceptibility to the disease.For a small subset of ad cases known as familial alzheimer's disease, genetic factors have been identified.This rare form of ad is linked to a mutation in one of several genes involved in betaamyloid production.For this group, the disease strikes earlier in life, commonly between 50 and 65 years of age, but can be.
Shoulder Arthritis Narrated Animation
The main joint of the shoulder is the joint between the head of the humerus the upper arm bone, and the glenoid cavity of the scapula the shoulder blade.This is a ballandsocket type of joint.Shoulder arthritis refers to loss of cartilage on the surface of the humeral head and the glenoid of the shoulder joint.The two bones rub against each other and produce pain, stiffness and difficulty moving an arm.Types of shoulder arthritis include osteoarthritis also called degenerative joint disease is the wear and tear condition of the joint, commonly due to old age.Osteoarthritis.
Is characterized by loss of cartilage, bone spurring and no major inflammation.Rheumatoid arthritis is a result of inflammation of the synovium the membrane that encloses the joint.Inflammation brings in the cells of the immune system, whose inflammatory chemicals damage and destroy the joint.It is not clear how rheumatoid arthritis starts but genetic predisposition together with infection of the joint are likely to be among the causes.Rotator cuff arthropathy or cuff tear arthropathy is shoulder arthritis as a result and in a setting of rotator cuff tears.Rotator cuff muscles hold the ball and the socket together.
And prevent the humeral head from moving out of the socket when the person raises an arm.In people with torn rotator cuff, the head of the humerus moves upwards and rub onto the acromion.This causes damages to the covering cartilage and eventually arthritis.Combination of cuff tear and arthritis is a devastating condition that seriously impairs functions of the shoulder joint.Posttraumatic arthritis is arthritis that develops after physical injury to the joint.Chondrolysis sudden loss of cartilage that happens occasionally after a shoulder surgery, commonly seen in association with infusion of local anesthetics into the joint for pain.
Smart Relief Ultimate II More Power Faster Relief
Do you suffer from chronic pain sore muscles are you tired of looking for relief in the wrong places well look no further! smart relief ultimate 2 is an advanced neuro stimulator that can be used to help relieve pain, anytime, anywhere.It is the same technology used by health professionals, like physical therapists and chiropractors.Smart relief ultimate 2 is an allinone device that offers tens and ems benefits to stimulate both nerve endings and muscles.T.E.N.S stands for transcutaneous electrical nerve stimulation tens it is most often used to help with muscle,.
Joint, or bone problems that occur with conditions such as sciatica, lower back pain, neck pain, shoulder pain, knee discomfort, tendinitis, bursitis, or with illnesses such as osteoarthritis or fibromyalgia.E.M.S.Stands for electrical muscle stimulation, also known as neuromuscular electrical stimulation.It works by eliciting muscle contractions using electric impulses.Ems has received increasing attention in the last few years because of its potential to serve as a strength training tool for healthy subjects, as well as a postexercise recovery tool for athletes.Smart relief ultimate 2 comes fully equipped with a digital display and backlit screen.
That is clear and easy to read.It offers 10 unique massage therapies that effectively target your pain.It has 20 levels of intensity that allow you to personalize your therapy and an adjustable timer for added convenience.Independently controlled dual outputs support up to four pads at once, providing relief to multiple areas at the same time.A longlasting rechargeable lithium battery provides many sessions on one single charge.The unit is backed by a 2year factory warranty and there is a lifetime warranty available for purchase.It is compact and easy to travel with.Bring home the most advance neuro stimulator.
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Alzheimers Disease AD Pathology And Genetics Animation
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